Doctor’s Best Glucosamine Chondroitin with MSM Supplement Review

Doctor’s Best Glucosamine is a blend of ‘The Big Three’ ingredients that have shown to be beneficial to joint health, structure, and function; Glucosamine Sulfate 2KCI, Chondroitin Sulfate, and MSM (Methylsulfonylmethane from OptiMSM).

But how does the dosage compare to other top rated Glucosamine supplements from big names like Kirkland Signature, Dr. Tobias, and Zenwise Labs?

In this review we’ll find out whether the ratio of ingredients found in Doctor’s Best Glucosamine is optimal for the health of your joints and cartilage, and whether it can be effectively used in the treatment or prevention of Osteoarthritis.

We’ve also made some important comparisons between the Doctor’s Best product, and two other top-rated Glucosamine supplements; Dr. Tobias Hip Knee and Joints, and Zenwise Labs Joint Support (Pro-Mobility Formula). This includes the price, ingredients, dosage, and customer feedback, and is designed to make sure you only buy the best Glucosamine for your health requirements and budget.

Doctor’s Best Glucosamine Ingredients

Doctor's Best Glucosamine Ingredients

A quick look at the ingredients for Doctor’s Best Glucosamine shows the capsules aren’t suitable for vegetarians or vegans. Gelatin has been used in the creation of the capsules, which also contain shellfish (crab, shrimp, lobster, crayfish).

However, you do have a combination of glucosamine sulfate (1500 mg) and chondroitin sulfate (1200 mg). Studies have shown this to be far more effective than glucosamine HCL and chondroitin, or glucosamine sulfate taken in isolation.

Each 4-capsule serving also contains 1,000 mg of MSM, from OptiMSM™. Although studies have proven this to be effective in the treatment of osteoarthritis, we’re hesitant to recommend OptiMSM™ for exercise-induced muscle and joint pain.

A study of runners completing a half-marathon found that MSM supplementation did lower both short-term (15 minute) and longer-term (1 day) muscle pain. But the same study (part-authored by Eric D Withee, employee at Bergstrom Nutrition, manufacturers of OptiMSM™) also concluded that more research on MSM and post-exercise pain on larger samples was needed.

Doctor’s Best Glucosamine is non-GMO, gluten free, and soy free, but carries an allergen warning due to the shellfish content. Not suitable for vegetarians/vegans due to the gelatin in the capsules.

Other ingredients: Potassium 182 mg, chloride 168 mg, sodium 56 mg.

Doctor's Best Glucosamine Chondroitin with MSM Supplement

Doctor’s Best Glucosamine – Product Summary

  • Serving size: 4 capsules
  • 60 servings per container
  • Doctor’s Best Glucosamine/Chondroitin/MSM featuring OptiMSM supports joint structure, function and comfort
  • A potent combination of three proven, purified ingredients that help build the cushy cartilage that serves as a shock absorber for your joints
  • Each serving provides 750mg of glucosamine sulfate, 600mg of chondroitin sulfate, and 500mg of MSM
  • Non-GMO and Gluten Free

Health benefits of Doctor’s Best Glucosamine

For a comprehensive list of glucosamine health benefits, we recommend our Glucosamine Buying Guide.

When is the best time to take it?

Recommended use

Take 4 capsules daily, with or without food, or as recommended by a nutritionally-informed physician.

Doctor’s Best vs. Zenwise Labs Joint Support

Doctor’s Best Glucosamine
Zenwise Labs Joint Support
Count per bottle: 240
Count per bottle: 180
Days of use: 60
Days of use: 60
Type of glucosamine: Sulfate
Type of glucosamine: Sulfate
Glucosamine: 1500 mg
Glucosamine: 1500 mg
Chondroitin: 1200 mg
Chondroitin: 1200 mg
MSM: 1000 mg
MSM: 1000 mg
Cost per serving: $0.43
Cost per serving: $0.40

Doctor’s Best vs. Dr. Tobias Glucosamine

Doctor’s Best Glucosamine
Dr. Tobias Glucosamine
Count per bottle:240
Count per bottle: 240
Days of use: 60
Days of use: 48
Type of glucosamine: Sulfate
Type of glucosamine: Sulfate
Glucosamine: 1500 mg
Glucosamine: 1500 mg
Chondroitin: 1200 mg
Chondroitin: 1200 mg
MSM: 1000 mg
MSM: 2000 mg
Cost per serving: $0.43
Cost per serving: $0.45

What sizes are available?

With a serving size of 4 capsules, each bottle provides you with either 30 or 60 servings. You can also find multi-pack deals on the larger 240 count bottles, but in our experience, they don’t offer the best value for money.

At the time of writing this review, the best value for money comes from the bottle of 240 capsules. Each serving was priced at $0.11, compared to $0.16 per serving with the bottle of 120.

We always recommend calculating the average cost per serving, across all sizes, before making a final buying decision.

Save money with Amazon

If you’re looking to save money on your monthly supplement order, you might want to consider the Amazon Subscribe & Save program.

Subscribe & Save allows you to unlock savings of up to 15% on a wide range of sports nutrition products, including Doctor’s Best Glucosamine.

You can save 5% with a subscription to 1 product, or save the full 15% by subscribing to 5 products, provided they’re all delivered to the same address. The delivery schedule can be set from monthly, up to once every 6 months.

Although 5 products might sound a lot, if you already supplement with a protein powder, multivitamin, creatine, BCAA, and glutamine, the savings can soon add up. But it’s best to order before you run out of your current supplements, because Amazon set the day of the month each order is sent (same day each month e.g. 14th.).

Who are Doctor’s Best?

Doctor’s Best is a nutritional supplement company based in San Clemente, founded by physician Ken Halvorsrude in 1990. They now offer more than 200 products, which only contain proven ingredients based on scientific research.

Doctor’s Best supplements range from simple vitamins to specialist products, such as Flavonoid Complex with Sytrinol for maintaining cholesterol levels.

To manufacture these supplements, Doctor’s Best only use cGMP-certified facilities and high quality raw material vendors, including Bergstrom Nutrition (OptiMSM) and Albion Minerals. This is part of their collaboration with nutritional scientists, to help develop and source the most effective ingredients to provide the results you want.

Glucosamine Buying Guide

Review Overview

Overall Review Rating

5 / 5

Doctor's Best Glucosamine has everything you could hope for from a joint health supplement. You have the clinically proven 1,500 mg of glucosamine sulfate, combined with chondroitin and MSM to help relieve joint pain and inflammation.

The fact that gelatin is used in the capsules isn't such a big deal, as glucosamine derived from shellfish is unsuitable for vegetarians anyway. You can also choose from a 1 month or 2 month supply, which can be a great way to save money.

Even as a company, Doctor's Best are one of the most respected in the industry, with high quality ingredients (OptiMSM) and cGMP certified manufacturing processes.

In terms of value for money, Doctor's Best Glucosamine is towards the upper end of the industry average for the ingredients used ($0.40 - $0.50 per day).

Dr. Tobias has a Hip Knee & Joints supplement that delivers the same amount of glucosamine and chondroitin, with twice as much MSM. The price fluctuates, but we have seen this on sale for less than Doctor's Best, so it's certainly worth checking the price of both before you buy.