Isopure Zero Carb Protein Powder Supplement Review

Isopure Zero Carb provides you with 50 g of protein, 0 g of carbohydrates, 0.5 g of fat, and 210 calories per serving. This also includes a complete stack of minerals, vitamins, and nutrients, such as Vitamin A (50% RDA), Vitamin C (50% RDA) and Calcium (70% RDA).

So when you combine this with the 4.6 g of L-Glutamine per serving, how does it measure up to other top-rated protein powder supplements?

In this review we’ll compare Isopure Zero Carb to two of the best low-carb protein powders, designed to assist with the development and maintenance of lean muscle. These are; Bulk Supplements Whey Protein Isolate (less than 1 g carbs), and Optimum Nutrition 100% Whey (3 g carbs). Comparisons include price, ingredients, dosages, cost per serving, flavors, and customer feedback, to help you find the best low carb protein for your fitness routine and diet.

We’ve also added recommendations for the best way to stack Zero Carb with pre-workout and creatine supplements to maximize your results, even on a strict budget.

Isopure Zero Carb Ingredients

Isopure Zero Carb Ingredients

Isopure Zero Carb protein powder has the same macronutrient profile as their hugely popular Whey Protein Isolate powder. Both have 25 g of protein per scoop, with no carbs or fat.

So, what’s the difference?

Zero Carb has a much more impressive micronutrient profile. Each serving (2 scoops) includes 50% of your daily value for over 20 vitamins, minerals, and antioxidants. Vitamins A, C, E, K, B6, B12, biotin, zinc, and calcium are just a few of those listed.

That means with two protein shakes per day, you’re getting the full 100%, in a blend that’s designed to naturally boost energy levels and improve your overall health.

We want to emphasize how rare it is to find a protein powder that almost doubles as a multivitamin. Optimum Nutrition has two protein powders that do this well (Serious Mass Gainer and Pro Gainer), but they’re both high in carbs and designed for someone looking to gain weight.

Muscle Milk does a better job, but still only provides an average of 35% DV for each vitamin and mineral, compared to the 50% found in Zero Carb. Carb levels are still a little high, with 19 g per serving, and 32 g of protein.

If you’re looking for a whey isolate protein powder that’s also high in vitamins and minerals, Zero Carb would have to be our top recommendation.

Vitamin and mineral blend (2 scoops, 1 serving)

  • Vitamin A 50%
  • Calcium 60%
  • Vitamin C 50%
  • Vitamin E 50%
  • Thiamin 50%
  • Vitamin K 50%
  • Riboflavin 50%
  • Niacin 50%
  • Vitamin B6 50%
  • Folate 50%
  • Vitamin B6 50%
  • Folate 50%
  • Vitamin B12 50%
  • Biotin 50%
  • Pantothenic Acid 50%
  • Phosphorus 50%
  • Iodine 50%
  • Magnesium 50%
  • Zinc 50%
  • Selenium 50%
  • Copper 50%
  • Manganese 50%
  • Chromium 50%
  • Molybdenum 50%
  • Chloride 20%

Zero Carb is also an excellent way to boost your protein intake without unwanted fat or carbs. This could be as part of a strict low-carb diet, such as Atkins or the ketogenic diet, or if you’re looking to lose fat and retain lean muscle, as part of a complete fitness and nutrition program.

Other ingredients listed on the label include xanthan gum, natural and artificial flavors, sucralose as a sweetener, and soy lecithin to improve mixability. Zero Carb contains no acesulfame potassium, which is another type of sweetener commonly found in protein powders.

Isopure Zero Carb Protein Powder

Isopure Zero Carb – Product Summary

  • 50 grams of 100% ion exchange whey protein isolate per serving
  • Zero Sugar
  • Lactose Free
  • Glutamine enriched loaded with BCAAs
  • Aspartame Free

When is the best time to take it?

Mix 2 scoopfuls (61 g) with 12 fluid ounces of water in a shaker or blender. Mix with slow release carbs for a complete pre-workout meal, or any day you need a quick and clean boost to your protein intake.

Zero Carb vs. Bulk Supplements Whey

Isopure Zero Carb
Bulk Supplements Whey
Protein: 50 g
Protein: 27 g
Carbohydrates: 0 g
Carbohydrates: 1 g
Fat: 0.5 g
Fat: 1 g
Calories: 210
Calories: 115
Protein density: 81%
Protein density: 90%
Container size: 3410 g
Container size: 1000 g
Serving size: 62 g
Serving size: 30 g
Cost per serving: $1.70
Cost per serving: $0.94

Zero Carb vs. O.N. 100% Whey

Isopure Zero Carb
Optimum Nutrition 100% Whey
Protein: 50 g
Protein: 24 g
Carbohydrates: 0 g
Carbohydrates: 5 g
Fat: 0.5 g
Fat: 1 g
Calories: 210
Calories: 120
Protein density: 81%
Protein density: 75%
Container size: 3410 g
Container size: 2250 g
Serving size: 62 g
Serving size: 30 g
Cost per serving: $1.70
Cost per serving: $0.78

What flavors and sizes are available?

Isopure Zero Carb is available in 4 different sizes; 1 pound (7 servings), 3 pounds (22 servings), 7.5 pounds (55 servings), and 8.8 pounds (46 servings). As you might expect, the larger the size, the more money you save per serving.

For the largest 8.8 lb tub you’re paying roughly $12.05 per pound, whereas the 1 lb bag costs $15.96 (prices correct at time of writing). Unfortunately, not all sizes will be available for all flavors, and prices tend to vary slightly between flavors. But with 16 to choose from, we’re confident you can save money and still enjoy a great tasting protein shake.


  • Alpine Punch
  • Apple Melon
  • Banana Cream
  • Columbian Coffee
  • Cookies and Cream
  • Creamy Vanilla
  • Dutch Chocolate
  • Espresso
  • Mango Peach
  • Mint Chocolate Chip
  • Natural Chocolate
  • Natural Vanilla
  • Pineapple Orange Banana
  • Strawberries & Cream
  • Toasted Coconut
  • Unflavored

Save money with Amazon

If you’re looking to save money on your monthly protein powder order, you might want to consider the Amazon Subscribe & Save program.

Subscribe & Save allows you to unlock savings of up to 15% on a wide range of supplements, including Isopure Zero Carb Protein Powder.

You can save 5% with a subscription to 1 product, or save the full 15% by subscribing to 5 products, provided they’re all delivered to the same address. The delivery schedule can be set from monthly, up to once every 6 months.

Although 5 products might sound a lot, if you already supplement with a protein powder, multivitamin, creatine, BCAA, and glutamine, the savings can soon add up.

Who are Isopure?

For over 30 years Isopure has specialized in nutritional supplements that deliver the cleanest and purest high quality protein. This means using 100% whey protein isolate that’s lactose-free, with little or no fats or carbs.

Their current line of protein powders is designed to help you bulk up, gain lean muscle, increase strength, or lose weight, depending on the product. Popular bestsellers include Isopure Mass and Isopure Zero Carb – 25 grams of whey protein isolate per scoop, available in 16 flavors.

RTDs are also available that deliver many of the same nutritional benefits. Isopure Mass RTD provides you with 53 grams of carbs, 8.9 grams of BCAAs, and 35 grams of protein in every 20 oz bottle.

In addition to their protein powders and drinks, Isopure also develop their own creatine monohydrate, aminos, and L-glutamine supplements. Isopure are a company under the Nature’s Best brand.

Protein Powder Buying Guide

Review Overview

Overall Review Rating

5 / 5

At the time of writing this review, each 62 gram serving of Isopure Zero Carb was priced at $1.75, based on buying a 3 pound tub. That’s high, even for a whey isolate protein powder.

However, if you consider that 1 scoop (32 grams) delivers 25 grams of protein, then you should cut that cost-per-serving in half if you want to compare against other whey isolate powders.

So for a single scoop of Zero Carb, the price was around $0.87. That’s still slightly higher than a serving of Isopure Whey Protein Isolate ($0.81 per serving, from the 3 pound tub), but you’re also getting a complete multivitamin and mineral complex.

The bestselling ISO 100 Whey Isolate Powder from Dymatize also delivers 25 grams of protein per serving, but at a cost of $1.11 (3 pound tub). So in comparison, Zero Carb is actually very reasonably priced.

Is it the cheapest whey isolate powder on the market? Not quite. We’ve seen some price closer to $0.78 per serving (NOW Sports Whey Protein Isolate), but only if you buy the largest 5 pound tubs. These cheaper powders are also missing the vitamins and minerals of Zero Carb, which is why it’s currently the best whey isolate protein on the market.